Research Article: Evaluation of the Antioxidant Interactions Between Green Tea Polyphenols and Nonsteroidal Anti-inflammatory Drugs

Author: Krystyna Pyrzynska

Journal: Open Chemistry Journal

Abstract:

Introduction:

The antioxidant interactions between the commonly used pharmaceuticals (diclofenac, ibuprofen and naproxen) and green tea polyphenols were evaluated.

Methods:

The antioxidant properties of the mixtures were evaluated by a scavenging effect on the 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical.

Results:

The mixtures contained green tea extract and each drug exhibited lower antioxidant activity than the mathematical sum of the results obtained for individual components showing antagonistic effect. The results were obtained using isobolographic analysis and interaction factors also suggested the antagonistic type of interaction. Only when the concentration of the green tea infusion was relatively high (in comparison to the drug), an additive effect could be concluded.

Conclusion:

The high concentration of green tea infusion in comparison to the drug should be used in developing the new formulations as it can help in the therapy due to their antioxidant properties.

To access this article, please visit:

https://benthamopen.com/ABSTRACT/CHEM-6-47

 

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Research Article: T1 and T2 Mappings in the Early Diagnosis of Achilles Tendinosis

Author: Zeineb Tbini

Journal: Open Medicine Journal

Abstract:

Objective:

The purpose of this study was to compare T1 and T2 relaxation times of normal and pathologic Achilles Tendon (AT) in order to evaluate the ability of these methods to detect early Achilles tendon tendinosis.

Materials and Methods:

Forty-eight subjects were included in this study. Twenty-two subjects were classified as normal group and twenty-six subjects as patient group with tendinosis. MR examination was performed by 3 Tesla scanner using a 12 channel head coil. For relaxation times quantification, we used a sagittal 3D FLASH variable flip angle gradient echo UTE sequence (3D VFA-GE UTE) for T1 mapping and a sagittal Multi Echo Spin Echo sequence (MESE) for T2 mapping. Relaxation times were quantified using two different algorithms written in MATLAB. P value < 0.05 was considered statistically significant.

Results:

Our results showed a statistically significant difference in T1 and T2 values for the normal group compared to the patient group (p<0.05). Mean values of T1 and T2 were 571.69 ms and 24.16 ms for the normal group and 818.10 ms and 32.43 ms for the patient group, respectively. Results reported no correlation (r=0.193) for T1 mapping and a positive significant moderate correlation (r=0.542, p=0.000) for T2 mapping between the normal and patient groups. T1 and T2 showed no correlation in the normal group (r= 0.091, p=0.489) and a positive significant weak correlation in the patient group (r=0.263, p=0.048).

Conclusion:

We concluded that T1 and T2 relaxation times are relatively sensitive to diagnosis degenerative changes in the AT and T1 is more sensitive to AT tendinosis compared to T2.

To access this article, please visit:

https://benthamopen.com/ABSTRACT/MEDJ-6-83

 

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Research Article: Effects of the Sea Breeze Circulation on Soil Temperature Over Kuwait Using in Situ Observations and the ECMWF Model

Author: Hussain Alsarraf

Journal: The Open Atmospheric Science Journal

Abstract:

Background:

The mesoscale circulation over Kuwait is an important influence on changes in surface temperatures and soil temperatures.

Introduction:

This paper presents two common summertime atmospheric features over Kuwait linking wind circulation to soil temperatures.

Methods:

In this study, we use the European Centre for Medium-range Weather Forecasts ECMWF reanalysis ERA-Interim dataset to investigate effects of the synoptic scale and mesoscale circulations.

Results:

The results show that a large-scale pressure gradient in summer typically leads to northerly winds over Kuwait, while a weak synoptic-scale pressure gradient leads to light easterly humid winds from the Persian Gulf, consistent with a mesoscale circulation.

Conclusions:

The results demonstrate the significance of wind circulations in driving the Soil Temperature (SOILT). Using the Era-Interim/Land reanalysis dataset for August 2015 over Kuwait, the average SOILT on days of sea breeze is higher than the average SOILT on days dominated by a synoptic-scale pressure gradient.

To access this article, please visit:

https://benthamopen.com/ABSTRACT/TOASCJ-13-29

 

TOASCJ-13-29_F1.jpg

Call for Papers | The Open Biomaterials Journal

Bentham Open is pleased to announce the launch of new open access journal, The Open Biomaterials Science Journal. The first volume of the journal will be available online by the start of the year, 2020.

The Open Biomaterials Science Journal is an Open Access online journal, which publishes research articles, reviews/mini-review, letters, case reports and guest edited single topic issues in all areas of biomaterials, biomedical device application, bioengineering, tissue engineering and medical items.

  • Medical Materials
  • Management of Device
  • Structural Biomaterials applied to Medicine
  • Orthopedic or Dental Implants
  • Oral Surgery
  • Maxillofacial Surgery
  • Plastic Surgery device
  • Operative Medicine
  • Fixed and Removable Prosthodontics
  • Biomaterials Science
  • Clinical Trials
  • Translational Research

The Open Biomaterials Science Journal a peer-reviewed journal, is an important and reliable source of current information on important recent developments in the field. The emphasis will be on publishing quality papers rapidly and freely available to researchers worldwide.

Each peer-reviewed article that is published in a Bentham OPEN Journal is universally and freely accessible via the Internet in an easily readable and printable PDF format.

All articles would be published FREE and no open access fee will be charged if submitted by December 31st, 2020.

To submit your paper, email at: beena@benthamopen.net and CC: faizan@benthamopen.net

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Become an Editorial Board Member (EBM) | BENTHAM OPEN JOURNALS 2020

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BECOME AN EDITORIAL BOARD MEMBER FOR THE OPEN JOURNALS

Bentham Opem is interested in appointing active Editorial Board Members on the Board for New journals listed below. If you are working in the related field as of the journals and are interested in becoming an Editorial Board Member, please send us your CV and a list of publications. If, however, the scope of the journal is not directly related to your field, you can recommend suitable colleagues for the same, and, if possible, send their CV along with their list of publications. Mention in the subject line the field of interest and send your CV at: beena@benthamopen.net and CC: faizan@benthamsopen.net

Become a Reviewer | BENTHAM OPEN JOURNALS 2020

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BECOME A REVIEWER FOR THE  OPEN JOURNALS

Bentham Opem is interested in appointing active Reviewers on the Board for New journals listed below. If you are working in the related field as of the journals and are interested in becoming a Reviewer, please send us your CV and a list of publications. If, however, the scope of the journal is not directly related to your field, you can recommend suitable colleagues for the same, and, if possible, send their CV along with their list of publications. Mention in the subject line the field of interest and send your CV at: beena@benthamopen.net and CC: faizan@benthamsopen.net

Research Article: Effects of the Sea Breeze Circulation on Soil Temperature Over Kuwait Using in Situ Observations and the ECMWF Model

Author: Hussain Alsarraf

Journal: The Open Atmospheric Science Journal

Abstract:

Background:

The mesoscale circulation over Kuwait is an important influence on changes in surface temperatures and soil temperatures.

Introduction:

This paper presents two common summertime atmospheric features over Kuwait linking wind circulation to soil temperatures.

Methods:

In this study, we use the European Centre for Medium-range Weather Forecasts ECMWF reanalysis ERA-Interim dataset to investigate effects of the synoptic scale and mesoscale circulations.

Results:

The results show that a large-scale pressure gradient in summer typically leads to northerly winds over Kuwait, while a weak synoptic-scale pressure gradient leads to light easterly humid winds from the Persian Gulf, consistent with a mesoscale circulation.

Conclusions:

The results demonstrate the significance of wind circulations in driving the Soil Temperature (SOILT). Using the Era-Interim/Land reanalysis dataset for August 2015 over Kuwait, the average SOILT on days of sea breeze is higher than the average SOILT on days dominated by a synoptic-scale pressure gradient.

To access this article, please visit:

https://benthamopen.com/ABSTRACT/TOASCJ-13-29

 

TOASCJ-13-29_F1.jpg

Research Article: Training and Evaluation of Community Health Workers (CHWs): Towards Improving Maternal and Newborn Survival in an Urban Setting in KwaZulu-Natal, South Africa

Author: Thoko Ndaba

Journal: The Open Public Health Journal

Abstract:

Background:

In South Africa, Community Health Workers (CHWs) are a key component of community outreach teams as part of Primary Health Care (PHC) re-engineering. Although the value of CHW programs has been increasingly recognized, published evaluations of CHWs’ training programs are rare. This study documents the training and evaluation of CHWs on maternal and neonatal care towards improved maternal-newborn survival in an impoverished urban setting in KwaZulu-Natal, South Africa.

Methods:

Using a descriptive study design, CHWs were trained to do home visits, assess and support the mother to settle in well at home post-discharge, check on babies’ warmth, cord care, breastfeeding, basic hygiene, size of the baby if underweight and advise on Kangaroo mother care. They were also trained to check if the mothers were given the Road to Health card and to inquire about the immunization and subsequent follow-up visits to the PHC, and encourage mothers to adhere to their follow up dates at PHC clinics. Pre-and post-test scores, shadow visits, and spot checks were used to evaluate their performance.

Results:

Generally, CHWs (n=47) from all three PHC clinics performed well. Overall, the highest post-test score among the PHC CHWs was 72% and the lowest was 50%. On average during shadow visits 67% CHWs were rated as good, 2% were rated as poor, and most CHWs received the highest score at 92% during spot checks.

Conclusion:

CHWs demonstrated social commitment and purpose in the short term observed. The evaluation of the training of CHWs revealed that most demonstrated the necessary skills for referrals to prevent complications, caring for newborns and their mothers at home immediately after discharge from health care centers. CHW upskilling training on maternal-newborn services should be prioritized in the most affected areas.

To access this article, please visit:

https://benthamopen.com/ABSTRACT/TOPHJ-12-406

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Research Article: Integrated Reservoir Characterisation for Petrophysical Flow Units Evaluation and Performance Prediction

Author: Annan Boah Evans

Journal: The Open Chemical Engineering Journal

Abstract:

Introduction:

An improved understanding of complex clastic reservoirs has led to more detailed reservoir description using integrated approach. In this study, we implemented cluster analysis, geostatistical methods, reservoir quality indicator technique and reservoir simulation to characterize clastic system with complex pore architecture and heterogeneity.

Methods:

Model based clustering technique from Ward’s analytical algorithm was utilised to transform relationship between core and calculated well logs for paraflow units (PFUs) classification in terms of porosity, permeability and pore throat radius of the reservoir. The architecture of the reservoir at pore scale is described using flow zone indicator (FZI) values and the significant flow units characterized adopting the reservoir quality index (RQI) method. The reservoir porosity, permeability, oil saturation and pressure for delineated flow units were distributed stochastically in 2D numerical models utilising geostatistical conditional simulation. In addition, production behaviour of the field is predicted using history matching. Dynamic models were built for field water cut (FWCT), total field water production (FWPT) and field gas-oil-ratio (FGOR) and history matched, considering a number of simulation runs.

Results:

Results obtained showed a satisfactory match between the proposed models and history data, describing the production behaviour of the field. The average FWCT peaked at 78.9% with FWPT of 10 MMSTB. Consequently, high FGOR of 6.8 MSCF/STB was obtained.

Conclusion:

The integrated reservoir characterisation approach used in this study has provided the framework for defining productive zones and a better understanding of flow characteristics including spatial distribution of continuous and discrete reservoir properties for performance prediction of sandstone reservoir.

To access this article, please visit:

https://benthamopen.com/ABSTRACT/TOCENGJ-13-97

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