RESEARCH ARTICLE: Prognostic Value of Troponin I in COVID-19 Patients

Author: Alaa A. Ghaleb

Journal Name: The Open Cardiovascular Medicine Journal

Abstract

Introduction:

Corona Virus Disease (COVID -19) patients present mainly with respiratory manifestations and viral pneumonia. The cardiovascular system presentation includes early signs of acute myocardial injury. Cardiac troponin I (cTnI) is a gold-standard biomarker for necrosis and myocardial risk assessment.

Aim of the work:

This study aimed to assess the prognostic value of cTnI in COVID-19 patients.

Methodology:

We report a prospective study that included 92 COVID-19 patients admitted to the El Helal Hospital, Sohag, Egypt. Upon admission, routine investigations including cTnI, chest Computed Tomography (CT), and Electrocardiogram (ECG) were carried out. The patients admitted to the intensive care unit (ICU) also had echocardiography.

Results:

More than half of the patients (55.4%) were admitted to ICU; cTnI level was elevated in 30 patients (58.8%), of whom 17 died (56.7%). There were statistically significant differences regarding the relation between cTnI level, D-dimer and the need for ICU admission and death (p=0.001).

Conclusion:

We conclude that cardiac troponin I levels are a prognostic factor for ICU admission and mortality in COVID-19 patients.

To access this article, please visit:

https://benthamopen.com/ABSTRACT/TOCMJ-15-18

CASE REPORT: Epinucleus Scraping: Safe New Phacoemulsification Technique for Rock-Hard Cataracts

Author: Aki Kondo

Journal Name: The Open Ophthalmology Journal

Abstract

Introduction:

Phacoemulsification of rock-hard cataracts is challenging because the leathery epinucleus at the posterior plate often found in such cataracts tends to prevent smooth dissection of the nucleus. We devised an Epinucleus scraping technique to overcome this problem.

Methods:

The epinucleus is initially stripped of the hard endonucleus using a new instrument. The isolated endonucleus can then be readily chopped and divided with a phaco chopper or in the usual manner.

Conclusion:

Phacoemulsification of rock-hard cataracts can be carried out safely and easily with epinucleus scraping technique.

To access this article, please visit:

https://benthamopen.com/ABSTRACT/TOOPHTJ-15-21

REVIEW ARTICLE: Role of Warburg Effect in Cardiovascular Diseases: A Potential Treatment Option

Author: Niken Puspa Kuspriyanti

Journal Name: The Open Cardiovascular Medicine Journal

Abstract

Background:

Under normal conditions, the heart obtains ATP through the oxidation of fatty acids, glucose, and ketones. While fatty acids are the main source of energy in the heart, under certain conditions, the main source of energy shifts to glucose where pyruvate converts into lactate, to meet the energy demand. The Warburg effect is the energy shift from oxidative phosphorylation to glycolysis in the presence of oxygen. This effect is observed in tumors as well as in diseases, including cardiovascular diseases. If glycolysis is more dominant than glucose oxidation, the two pathways uncouple, contributing to the severity of the heart condition. Recently, several studies have documented changes in metabolism in several cardiovascular diseases; however, the specific mechanisms remain unclear.

Methods:

This literature review was conducted by an electronic database of Pub Med, Google Scholar, and Scopus published until 2020. Relevant papers are selected based on inclusion and exclusion criteria.

Results:

A total of 162 potentially relevant articles after the title and abstract screening were screened for full-text. Finally, 135 papers were included for the review article.

Discussion:

This review discusses the effects of alterations in glucose metabolism, particularly the Warburg effect, on cardiovascular diseases, including heart failure, atrial fibrillation, and cardiac hypertrophy.

Conclusion:

Reversing the Warburg effect could become a potential treatment option for cardiovascular diseases.

To access this article, please visit:

https://benthamopen.com/ABSTRACT/TOCMJ-15-6

CALL FOR THEMATIC ISSUES – The Open Respiratory Medicine Journal

Submit your Proposals at: madiha@benthamopen.net

Aims & Scope:

The Open Respiratory Medicine Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews, letters and guest edited single topic issues in all important areas of experimental and clinical research in respiratory medicine. Topics covered include:

  • COPD
  • Occupational disorders, and the role of allergens and pollutants
  • Asthma
  • Allergy
  • Non-invasive ventilation
  • Therapeutic intervention
  • Lung cancer
  • Lung infections respiratory diseases
  • Therapeutic interventions
  • Adult and paediatric medicine
  • Cell biology

The Open Respiratory Medicine Journal, a peer reviewed journal, is an important and reliable source of current information on important recent developments in the field. The emphasis will be on publishing quality articles rapidly and making them freely available worldwide.

The Open Respiratory Medicine Journal – BECOME A REVIEWER

Submit your CV at: madiha@benthamopen.com

Selection of Reviewers

The Editor-in-Chief (EiC) and Senior Editors of the journal together with the publication manager have the right to select reviewers for a particular manuscript considering the knowledge and experience of the reviewers.

Before sending the manuscripts to a reviewer, Bentham Open seeks consent from potential reviewers about their availability and willingness to carry out a review. The correspondence between the editorial office of the journal and reviewers is kept strictly confidential. The author does not know who has conducted the review on his or her manuscript (except in the case when the author and the reviewer have accepted to the “Open Reviewer Option”, in which case this information becomes available to the public after publication).

Important Points to Consider

Reviewers are expected to provide advice on the following points in their review reports:

  • Is the manuscript written comprehensively enough to be understandable? If not, how could it be improved?
  • Have adequate proofs been provided for the declarations?
  • Have the authors addressed the previous findings fairly?
  • Does the paper offer enough details of its methodology to reproduce the experiments?
  • Bentham Open encourages authors to publish detailed protocols as supporting information online. Do any particular methods used in the manuscript warrant such a protocol?

We look forward to your emails for becoming a reviewer.

Become an Ambassador – The Open Respiratory Medicine Journal

CALL FOR AMBASSADORS

Bentham Open invites researchers, scientists, faculty members, students and others relevant to join us as Bentham Open Ambassador. Following are the benefits and responsibilities of Bentham Ambassadors.

Submit your latest CV at madiha@benthamopen.net

Benefits Available to Bentham Open Ambassadors: 

  1. You will receive a Certificate of Acknowledgement for joining and rendering your services as a Bentham Open Ambassador
  2. As a Bentham Open Ambassador, you would have the possibility of having your first article published in any Bentham Open journal of your choice, at 50% discount on Open Access fee. For a listing of journals please refer to our website.   If you would refer more researchers to publish articles in our journals, we will be pleased to publish their articles at a 25% discount on our standard publishing rates.
  3. On earning 100 points you will be entitled to a 50% discount on the publication fee of your 2nd article and a full fee waiver for the 2nd article will be offered if you earn 200 points through your efforts to promote Bentham Open Publications.
  4. Your name and affiliation will be mentioned on a dedicated Bentham Open Ambassadors webpage, which will help you in your various promotional activities since your position will be visible for visitors on the website.
  5. As a Bentham Open Ambassador, you would have the possibility to get your institution listed as a Bentham Open Member Institute. An official request would be required from your institution for this. Being an author from the member institute(s), you and your colleagues (affiliated with the member institution) will receive a 50% special discount in the publication fee for your submission in Bentham Open journals and a centralized billing system for your institution can be developed. 
  6. We invite our Member Institutes to bear the Article Processing Charges (APCs) on behalf of their researchers. Each Member Institute is provided with a unique code for this provision. Affiliated researchers will need to mention this code while submitting an article.

 The responsibilities of Bentham Open Ambassadors would be to: 

  1. Introduce and promote Bentham Open journals among librarians, colleagues and researchers in your region.
  2. Encourage submission of articles to relevant Bentham Open journals, in your field, from eminent scientists.
  3. You may, if you wish, also appoint some young researchers as “Associate Bentham Open Ambassadors” to magnify this effort.

Become Executive Guest Editor – The Open Respiratory Medicine Journal

Bentham Open invites researchers to join as Executive Guest Editor for the journal, The Open Respiratory Medicine Journal.

The Open Respiratory Medicine Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews, letters and guest edited single topic issues in all important areas of experimental and clinical research in respiratory medicine. Topics covered include:

  • COPD
  • Occupational disorders, and the role of allergens and pollutants
  • Asthma
  • Allergy
  • Non-invasive ventilation
  • Therapeutic intervention
  • Lung cancer
  • Lung infections respiratory diseases
  • Therapeutic interventions
  • Adult and pediatric medicine
  • Cell biology

The Open Respiratory Medicine Journal, a peer reviewed journal, is an important and reliable source of current information on important recent developments in the field. The emphasis will be on publishing quality articles rapidly and making them freely available worldwide.

The Open Respiratory Medicine Journal – Join the Editorial Board

The Open Respiratory Medicine Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews, letters and guest edited single topic issues in all important areas of experimental and clinical research in respiratory medicine. Topics covered include:

  • COPD
  • Occupational disorders, and the role of allergens and pollutants
  • Asthma
  • Allergy
  • Non-invasive ventilation
  • Therapeutic intervention
  • Lung cancer
  • Lung infections respiratory diseases
  • Therapeutic interventions
  • Adult and paediatric medicine
  • Cell biology

Submit your CV at: madiha@benthamopen.com

The Open Respiratory Medicine Journal – CALL FOR PAPERS

Submit your Proposals at: madiha@benthamopen.net

The Open Respiratory Medicine Journal, a peer reviewed journal, is an important and reliable source of current information on important recent developments in the field. The emphasis will be on publishing quality articles rapidly and making them freely available worldwide.