NEWS RELEASE – Comparison of Early Postoperative Pain After First vs Second Total Knee Arthroplasty

News release- The Open Orthopaedics Journal

This article by Dr. Yoshinori Ishii et al. is published in The Open Orthopaedics Journal, Volume 14, 2020

Bentham Open Article: A Retrospective Comparison of Early Postoperative Pain after the First Vs Second TKA in Scheduled Staged Bilateral TKA

Acute postoperative pain control after Total Knee Arthroplasty (TKA) is important as the poorly controlled, persistent pain can cause delay in rehabilitation. The researchers define the purpose of this study to be the comparison of pain intensity during the early postoperative period (following the first and second surgeries) in patients who underwent bilateral, scheduled, staged TKAs.

The researchers enrolled 32 patients (64 knees) in this study and evaluated the number of requests for analgesic agents during the first 3 days after TKA, time to walking, and the Wong-Baker FACES pain assessment score (WBS).

Comparing the postoperative period post the first and second TKA, there were no significant differences in WBS 24, 48, and 72 hours postoperatively. The frequency of requests, and the total number of requests for analgesics did not differ when comparing the first and second TKA, at any interval. The total number of analgesic requests exhibited a moderately strong, positive correlation between the first and second TKA (p < 0.001, r = 0.623). Patients’ WBS scores and requests for analgesics showed a moderately strong, positive correlation, but only at 24 hours following the second TKA (p = 0.002, r = 0.567). After both TKAs, patients required a median of 1 day to resume walking.

Patients undergoing staged bilateral TKA experienced equivalent early postoperative pain when comparing their experience following their first and second TKAs. Therefore, regarding pain control following the second TKA, we recommend considering the analgesic administration schedule and requirements of the first TKA.

This article is open access and can be obtained from the following link:

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NEWS RELEASE – Evaluation of pedestrian walking speed change patterns at crosswalks in Palestine

News release- The Open Transportation Journal

The research article by Dr. Fady M. A. Hassouna is published in The Open Transportation Journal, Volume 14, 2020

Bentham Open Article: Evaluation of Pedestrian Walking Speed Change Patterns at Crosswalks in Palestine

The convenience and safety for pedestrians worldwide has been a topic gaining much attention, when we consider road designs, crosswalks, traffic signals and transportation regulations and infrastructure. The research study conducted by Dr. Fady M. A. Hassouna, from An-Najah National University, Nablus, Palestine, focuses on the pedestrian walking speed change patterns with reference to different factors related to pedestrian characteristics in Palestine. The factors that were considered included the age of the pedestrians, gender and crossing patterns based on traffic control at different locations, i.e. signalized and unsignalized crosswalks.

The researchers gathered data of crossing speeds for 4,301 pedestrians in a populous city of Palestine, Nablus. The data was taken from six different locations, of which three had traffic signals and three did not have traffic signals. Statistical analysis including Z-Test and ANOVA Test was conducted and certain significant results were found from the study.

The research concluded that male pedestrians walked significantly faster than female pedestrians. Considering the age, younger people turned out to be faster crossing pedestrians than the older generation, which was much anticipated. But the walking speed on crosswalks for unsignaled crosswalks compared to signaled crosswalks did not appear to be significantly high.

Lastly the research found the average and the 15 degree percentile for the pedestrians crossing the crosswalks. These figures were essential to design the facilities and traffic signals for the pedestrians.

This research article is open access and can be obtained from the following link:

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call for thematic issue covid 19

“The Open Biology Journal”

COVID-19 pandemic has spread throughout the world faster than wildfire, and has damaged the health of millions of people, claiming many lives.

We at Bentham Open endeavor to be in the frontline, alongside the world, to publish the best, latest research studies on COVID-19 and Coronavirus, and help eradicate this disease from the world. Our salient open access journal, The Open Biology Journal, welcomes proposals for Thematic Issues on COVID-19 and related topics from biologists, virologists, biotechnology experts and other researchers involved in research relevant to the topic.

Every article in the COVID-19 Thematic Issue will be published free of charge, as Open Access.

Submit your Thematic Issue Proposal at:


call for paper The Open Biology Journal

CALL FOR Papers! 💡
“The Open Biology Journal”

Bentham Open invites researchers, scientists, experts, academia and professionals engaged in Biology and related research projects to publish their articles in The Open Biology Journal, free of charge.

Aims & Scope of the Journal

The Open Biology Journal is an open access online journal, which publishes research, review/mini-review and letter articles and guest edited single topic issues, reviews and letters in all areas of biology and at the interface of related disciplines. The core disciplines in biology that are published in the journal are the following: Cell & Developmental Biology; Genetics & Genomics; Molecular Biology; Structural Biology; Bioinformatics; Systems Biology; Immunology; Biochemistry; Ecology; Zoology; Ornithology; Entomology; Marine & aquatic Biology; Plant Biology; Bioethics; Behavioural science ; Microbiology; Reproductive Biology; Glycobiology; Macromolecules; Proteins & Peptides; Theoretical & Mathematical Biology; Evolutionary Biology; Techniques in Biology; Biotechnology, Applied Microbiology, Biodiversity Conservation, Biophysics, Biostatistics, Crystallography of macromolecules., education in biology, Marine & Freshwater Biology, Mathematical & Computational Biology, Mycology, Nanoscience & Nanotechnology, Parasitology, Paleobiology, Astrobiology; Physiology, biopolymers, Soil biology, and Interdisciplinary Applications in biology.

The Open Biology Journal, a peer-reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality papers rapidly and freely available to researchers worldwide.

We welcome you to send your manuscripts at:

Call for Papers – The Open Biotechnology Journal

call for paper The Open Biotechnology Journal

CALL FOR Papers! 💡
“The Open Biotechnology Journal”

Bentham Open welcomes biotech researchers to publish their latest research in The Open Biotechnology Journal.

Aims & Scope:

The Open Biotechnology Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews and letters in all core areas of biotechnology including basic and applied research e.g. molecular engineering of nucleic acids and proteins, molecular therapy, imaging technology and large scale biology, regenerative medicine, analytical biotechnology, food and agricultural biotechnology and environmental biotechnology.

The Open Biotechnology Journal, a peer-reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality articles rapidly and freely available to researchers worldwide.

You can submit your manuscripts at:


Call for Papers – The Open Bioactive Compounds Journal

The Open Bioactive Compounds Journal

CALL FOR Papers! 💡
“The Open Bioactive Compounds Journal”


We welcome research and review articles to be published as Open Access in our journal, The Open Bioactive Compounds Journal. Here are the Aims and Scope of the journal:

Aims & Scope:

The Open Bioactive Compounds Journal is an Open Access online journal, which publishes original research articles, letters, review/mini-review articles, short articles and guest edited single topic issues on bioactive compounds.

The Open Bioactive Compounds Journal, a peer-reviewed journal, is an important and reliable source of current information on developments and research in new bioactive compounds with proven activities in various biological screenings and pharmacological models. The aim is to provide a valuable information source of bioactive compounds synthesized or isolated, which can be used for further development of pharmaceuticals by industry and academia. The emphasis will be on publishing quality papers rapidly and freely available to researchers worldwide, proving essential reading for pharmacologists, pharmaceutical chemists and medicinal chemists who wish to be kept informed and up-to-date with the latest and most important developments about new bioactive compounds of natural or synthetic origin, including recent patents.

Send us your manuscripts at:

Call for Papers – Open Access Model FREE of charge

The Open Food Science Journal

CALL FOR Papers! 💡
“The Open Food Science Journal”

★ Publish your article on Food Science in Open Access FREE of charge.  ★

Aims & Scope:
The Open Food Science Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews, letters and guest edited single topic issues in all important areas of food science and technology including but not limited to:

  • Food Chemistry, Microbiology and Safety
  • Food Engineering
  • Sensory Studies
  • Food Structure and Composition
  • Chemistry, Microbiology and Biotechnology aspects of food
  • Emerging Safety and Toxicological Issues
  • Proteomics, Metabolomics, Nutrigenomics and Chemogenomics of Foods Food Quality And Safety
  • Nutraceuticals, Functional Foods and Functional Ingredients
  • Biophysical analysis of Food / Processing Operations
  • Environmental safety and sustainability aspects of food processing
  • Waste / by-product management in food processing

The Open Food Science Journal, a peer-reviewed journal, is an important and reliable source of current information on recent important developments in the field. The emphasis will be on publishing quality papers rapidly and making them freely available to researchers worldwide.

Please send your proposal:

CALL FOR THEMATIC ISSUE – Submit Thematic Issue Proposal for Open Agriculture Journal

The Open Agriculture Journal

“The Open Agriculture Journal”

★ Bentham Open invites researchers related to Agricultuer and Food Science to submit Proposal for Thematic Issue related to the topic. ★

Aims & Scope:

The Open Agriculture Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews and letters in all areas of agricultural science. Topics covered include, agronomy; plant and animal breeding; genetics; agricultural biotechnology; crop physiology and agroecology; soil science and agroclimatology; agricultural economics and rural sociology; and sustainable systems. Agricultural biotechnology (including tissue culture, molecular markers, molecular diagnostics, vaccines, genetic engineering, genome editing as well as synthetic biology) to modify living organisms: microorganisms, fungi, plants and animals).

The scope of the journal includes but is not limited to:

  • Crop protection and Cultivation
  • Animal Science and Aquaculture
  • Pharmacognosy and Pharmaceutical Development
  • Environmental implications of agricultural land
  • Horticulture
  • Forestry
  • Agricultural Sciences, including Genetics and Agricultural Biotechnology
  • Environmental Sciences, including prevention and correction of adverse environmental effects (e.g., soil degradation, waste management, bioremediation)

Please send your proposal:

NEWS RELEASE -Online romance scams: A modern form of fraud


This article by Dr. Andrea Pozza et al. is published in Clinical Practice & Epidemiology in Mental Health, Volume 16, 2020


Over the last 20 years, the rapid development of digital communication technology has given rise to new forms of social interaction on social media. Digital communication technologies can overcome physical, social and psychological barriers in building romantic relationships. Around 1400, dating sites/chats have been created over the last decade in North America alone. Solely in the UK, 23% of Internet users have met someone online with whom they had a romantic relationship for a certain period and that even 6% of married couples met through the web.

While communication technologies have revolutionized, and continue to revolutionize, the modalities of interaction and the building of emotional attachment on the one hand, on the other, the online dating industry has given rise to new forms of pathologies and crime. Online romance scams are a modern form of fraud that have spread in Western societies along with the development of social media. Through a fictitious Internet profile, the scammer develops a romantic relationship with the victim for 6-8 months, building a deep emotional bond with the aim of extorting economic resources in a manipulative dynamic. There are two notable features: on the one hand, the double trauma of losing money and a relationship, on the other, the victim’s shame upon discovery of the scam, an aspect that might lead to underestimation of the number of cases. Sixty-three percent of social media users and 3% of the general population report having been a victim at least once. Women, middle-aged people, and individuals with higher tendencies to anxiety, romantic idealization of affective relations, impulsiveness and susceptibility to relational addiction are at higher risk of being victims of the scam. Understanding the psychological characteristics of victims and scammers will allow at-risk personality profiles to be identified and prevention strategies to be developed. This editorial can be obtained from the following link:

For more information please visit:

RESEARCH ARTICLE – Impact of a Health System’s Three-Pronged Strategy to Address the Opioid Epidemic in DE, PA, and WV, 2013-2017

Author: Oralia Dominic

Journal: The Open Public Health Journal



In the past two decades, from 1999-2017, more than 700,000 people have died from a drug overdose in the United States. In 2017, more than 68% of the drug overdose deaths involved an opioid, and the opioid death rate was six times higher than in 1999. Although treatable, opioid addiction has significant health consequences; and evidence-based, data-driven models addressing these opioid-related factors remain sparse.


To help stem this epidemic, Highmark Inc., a national health plan as well as the second largest integrated delivery and financing system in America, developed, implemented and evaluated a series of quality management-focused opioid interventions utilizing a three-pronged public health approach. We focused on more effectively managing pain to reduce the need for opioids (primary prevention); when needed, prescribing opioids according to safe prescribing guidelines (secondary prevention); and for those with Opioid Use Disorder (OUD), ensuring access to effective treatment to reduce morbidity/mortality (tertiary prevention) for our members.


We deployed a series of evidence-based and data-driven interventions utilizing clinical guidelines, integrated and coordinated infrastructures, and community-based participatory research frameworks within our service areas of Delaware, Pennsylvania, and West Virginia. We examined medical and pharmacy claims for combined data years 2013-2017 by age, product (commercial, diagnosis with OUD), total Opioid prescription (RX) fill rate (per 1,000 members), opioid use by dose (dosage level by Morphine Milligram Equivalents), opioid use by duration (number days of opioid use), rate per 1,000 members diagnosed with OUD, and geography.


Improvements in total Opioid RX fills, opioid use by dose and duration for members diagnosed with OUD. Over these years, a decrease of 19% of total Opioid RX fills; shorter durations and the majority of these members switched to 7 days or less of opioid use; and a reduction by 13 percentage point of the number of members on higher strength 20+ MMEs opioids resulted.


These findings may help inform nationwide opioid-focused efforts and set priorities.

To access this article, please visit: